Name | 1-Acetoxynaphthalene |
Synonyms | 1-naphthylacetae 1-NAPHTHYL ACETATE 1-Acetoxynaphthalene Naphthalenol, acetate alpha-naphtholacetate Naphthalene, 1-acetoxy- 1-naphthalenol, acetate naphthalen-1-yl acetate ACETIC ACID 1-NAPHTHYL ESTER aceticacidnaphthalen-1-ylester ACETIC ACID ALPHA-NAPHTHYL ESTER |
CAS | 830-81-9 |
EINECS | 212-599-8 |
InChI | InChI=1/C12H10O2/c1-9(13)14-12-8-4-6-10-5-2-3-7-11(10)12/h2-8H,1H3 |
Molecular Formula | C12H10O2 |
Molar Mass | 186.21 |
Density | 1.1032 (rough estimate) |
Melting Point | 43-46 °C (lit.) |
Boling Point | 118 °C / 1mmHg |
Flash Point | 113 °C |
Solubility | Soluble in ethanol. |
Vapor Presure | 0.000618mmHg at 25°C |
Appearance | Solid |
Color | White to light yellow or slightly pink |
Odor | Odorless |
BRN | 2046403 |
Storage Condition | -20°C |
Sensitive | Moisture Sensitive |
Refractive Index | 1.6010 (estimate) |
MDL | MFCD00003922 |
Physical and Chemical Properties | Melting Point: 43 - 46 |
Use | The substrate for the determination of α-esterase in enzyme chemistry. Colorimetric determination of insecticide degradation of carboxylesterase. Intermediates in organic synthesis. |
Risk Codes | R41 - Risk of serious damage to eyes R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R10 - Flammable |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S24/25 - Avoid contact with skin and eyes. S22 - Do not breathe dust. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. |
UN IDs | UN 1993 3/PG 3 |
WGK Germany | 3 |
RTECS | QL2975500 |
FLUKA BRAND F CODES | 10-21 |
TSCA | Yes |
HS Code | 29153900 |
Reference Show more | 1. Jiang Luye Lin, Yang, Xue, Li, Shanshan, Shen, Guanming, Zhang Zhiqing. Effect of different pretreatment on detection of organophosphorus and carbamate pesticide residues in vegetables by plant esterase inhibition method [J]. Food and Fermentation Industry, 2016, 42(01):200-204. 2. Niuwei, Zhang Cong, Chang Jing, et al. Carboxylase activity of bifenthrin-resistant Lycium barbarum aphid and inhibitory effects of four common insecticides [J]. Chinese Journal of pesticide science, 2017, 19(006):755-759. 3. Ye Lin, Jiang Lu, Shen Guanming, Li Shanshan, Wu Hejun, Zhang Zhiqing. Study on immobilization of wheat bran esterase on cellulose membrane [J]. Food and machinery, 2016,32(10):63-68. 4. Jiang Lu, Ye Lin, Yang Xue, etc. Sensitivity of wheat bran esterase to organophosphorus and carbamate pesticides [J]. Journal of Nuclear Agriculture, 2016, 30(005):934-940. 5. Niuwei, Zhang Cong, Li Qingyu, Li Haiping, xiqingyun. Characteristics of carboxylesterase from aphids of Lycium barbarum and inhibitory effect of insecticides [J]. Journal of Inner Mongolia Agricultural University (Natural Science Edition),2015,36(04):23-28. 6. Zhang Hang, Yang anpei, Bai Wei, Gao Haifeng, Li broad, Wang lock-in. Effects of sublethal concentrations of three insecticides on detoxification enzyme activities of larvae of Spodoptera exigua [J]. Pesticides, 2020,59(11):846-850. 7. Lin Ye, Xiang Liu, Guang-Hui Shen, Shan-Shan Li, Qing-Ying Luo, He-Jun Wu, An-Jun Chen, Xing-Yan Liu, Mei-Liang Li, Biao Pu, Wen Qin, Zhi-Qing Zhang, Properties comparison between free and immobilized wheat esterase using glass fiber film, International Jo 8. Ding, Jun-Nan, Hui-Hui Zhang, and De-Fu Chi. "Effects of a pathogenic Beauveria bassiana (Hypocreales: Cordycipitaceae) strain on detoxifying and protective enzyme activities in Xylotrechus rusticus (Coleoptera: Cerambycidae) larvae." Florida Entomologist 9. [IF=6.953] Lin Ye et al."Properties comparison between free and immobilized wheat esterase using glass fiber film."Int J Biol Macromol. 2019 Mar;125:87 |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
biological activity | 1-naphtyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-naphtyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning. |
Target | AChE |
Use | the product is hydrolyzed by α-esterase to precipitate α-naphthol, A colored azo dye formed from a heavy diazonium salt in 0.05m phosphate buffer, used in enzyme histochemistry for the assay of the enzyme A- enzyme. It is also used as an intermediate in organic synthesis. The substrate of α-tryptase was determined in Enzyme Chemistry. Colorimetric Determination of insecticide-degrading carboxylesterase. Organic synthesis intermediates |
production method | is obtained by reacting sodium 1-naphthol with acetic anhydride. |
category | toxic substances |
toxicity grade | poisoning |
Acute toxicity | oral-rat LD50: 1000 mg/kg |
flammability hazard characteristics | toxic gases emitted by heat |
storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
fire extinguishing agent | water, carbon dioxide, sand, foam |